Quarterback Bo Nix was central to Denver's success, delivering the best performance of his young career. Completing 28 of 37 passes for 284 yards, Nix threw three touchdown passes and added a rushing touchdown, earning a quarterback rating of 124.2. His ability to distribute the ball effectively was crucial, targeting multiple receivers throughout the game, which kept the Panthers' defense on their toes. This performance not only contributed significantly to the team's victory but also marked him as the winningest rookie quarterback in Broncos' history.

Denver's defense was a formidable force, with notable performances including Pat Surtain II's crucial interception and Nik Bonitto's consistent pressure on the quarterback, achieving his sixth consecutive game with a sack. The defense's ability to pin Carolina deep in their territory early in the game was a turning point, allowing Denver to capitalize and build momentum. Additionally, strategic plays such as a one-handed touchdown reception by Adam Trautman and a successful third-down conversion rate of 64.7% were key factors in maintaining control throughout the game.

The Carolina Panthers faced significant challenges, with a long list of injuries impacting their performance. Quarterback Bryce Young, despite a valiant effort, could not steer the team to victory, partly due to the absence of key players like wide receivers Diontae Johnson and Adam Thielen. The Panthers' offense struggled to maintain possession and failed to capitalize on the few opportunities they had, which was evident in their inability to score following the initial touchdown until the final moments of the game.