The Packers' strategy to focus on the ground game paid off handsomely, with running back Josh Jacobs delivering a standout performance by rushing for 151 yards. The team's total of 261 rushing yards was their highest in a single game since 2003. This run-heavy approach was pivotal, especially in the absence of Jordan Love, as Malik Willis made his first-career start. The offensive line, despite a peculiar moment where center Josh Myers vomited on the ball, was formidable, paving the way for the team's running success and controlling the clock effectively throughout the game.

The Indianapolis Colts faced a tough challenge against the Packers' robust defense. Despite a promising performance from running back Jonathan Taylor and a late touchdown, the Colts could not overcome the Packers' early lead. Green Bay's defense was crucial, securing three interceptions and a critical fumble recovery that prevented a Colts' touchdown. The defensive efforts were complemented by the Packers' ability to maintain possession and keep the Colts' offense off the field for extended periods.

This win was not just another tally in the season's win column for Green Bay; it was a historic moment marking the Packers' 800th victory, making them the first NFL team to reach such a milestone. The Packers have been a cornerstone of the NFL since their inception in 1921, and this victory is a testament to the enduring success and competitive spirit of the franchise. The strategic decision to rely on the running game in the absence of their starting quarterback showcased the team's adaptability and depth.